Conformation Changes, Complexation, and Phase Transition in Matrix-Assisted Laser Desorption

Solid-phase thermodynamic interpretation of ion desorption in matrix-assisted laser desorption/ionization.

This work demonstrates a quantitative interpretation of ion desorption in matrix-assisted laser desorption/ionization (MALDI). The theoretical modeling incorporates transition state theory for the desorption of surface ions, assuming chemical and thermal equilibrium in the solid state prior to desorption. It is distinct from conventional models that assume chemical equilibrium in the gas phase....

Matrix-Assisted Laser Desorption/Ionization (MALDI)

Matrix Assisted Laser Desorption Ionization Time

Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic review s. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts w ithin the time allow ed. Rapid responses should be considered along w ith other types of information and health care considerations. The information i...

Matrix-Assisted Laser Desorption/Ionization with ultrashort laser pulses

In our group, we perform successfully MALDI by using femtosecond laser techniques in order to examine the ionization process. One recent result is MALDI with ultrashort laser pulses in the near IR (central wavelength of =800 nm) [2]. In this wavelength regime, used matrix substances have no absorption bands. Experiments with different laser pulse durations suggest that multi photon ionization i...

Laser desorption and matrix-assisted laser desorption/ionization mass spectrometry of 29-kDa Au:SR cluster compounds.

Positive and negative ions generated by laser-based ionization methods from three gold:thiolate cluster compounds are mass analyzed by time-of-flight mass spectrometry. The three compounds have similar inorganic core masses ( approximately 29 kDa, approximately 145 Au atoms) but different n-alkanethiolate ligands associated with each cluster compound (Au:SR, R = butane, hexane, dodecane). Irrad...